Total number of AIDS-related deaths worldwide 2000-2023

UNAIDS estimated that there were some 630,000 people worldwide that died from acquired immune deficiency syndrome (AIDS) in 2023. This statistic depicts the total number of annual AIDS-related deaths worldwide from 2000 to 2023. 

HIV/AIDS burden

A majority of countries with the highest burden due to HIV and AIDS are in Africa- in 2023, the highest number of AIDS-related deaths occurred in South Africa and Nigeria and the highest prevalence of HIV was found in Eswatini. Although access to life-saving antiretroviral therapy treatment (ART) has increased globally over recent years, many individuals living with HIV still lack access to ART.

Barriers and interventions

In part due to the development of ART, the number of people living with HIV worldwide is continuing to increase, reaching almost 40 million in 2023. Important public health measures to combat the burden of the disease include a combination of biomedical and behavioral interventions such as pre- and post-exposure prophylaxis, and context-specific structural interventions to reduce barriers to supplies and education. One prominent barrier faced by those living with HIV is stigma, which can often cause disadvantages in many areas of life, including employment, use of health services, and social support.